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Our Mission

The Little p Project funds the development and advancement of research and viable treatment options for cancers similar to Parker's.

 

Funds raised will be used to further pediatric sarcoma research, assist in facilitating studies & trials, improve access & information, and help the desperate families currently fighting this disease.
 

Why we need your help
 

  • Cancer is the leading cause of death by disease in children.
     

  • Every 3 minutes, a child is diagnosed with cancer. Annually in the U.S., approximately 15,000 children are told they have cancer, meaning 1.5 million family members, friends, and classmates are directly impacted by pediatric cancer.
     

  • Despite these facts, childhood cancer research is underfunded. The National Cancer Institute (NCI) only spends an average of 4% of its research funding on all pediatric cancers combined.
     

  • Over 200 cancer drugs have been developed and approved for adults.  Specific to children, only 6 drugs have been approved for pediatric cancer.
     

  • Treatment protocols and therapies for pediatric sarcomas have not advanced in the past 30 years and remain centered around surgery, chemotherapy and radiation (commonly referred to as Cut, Poison, Burn. The options are limited and the response rate and survival for patients remains low. New protocols and therapies are desperately needed to improve the outcome for these pediatric cancer patients.
     

  • For many adult cancers, you have alternatives, and therefore time. For kids with unresponsive or relapsed soft tissue sarcoma, the alternatives are limited or non-existent.
     

  • The more research that is funded, the closer we are to find new innovative protocols & therapies that can save the lives of our pediatric sarcoma patients.  
     

About Sarcoma

  • Sarcoma is a broad term for malignant aggressive cancers that arise from bone and connective tissue (fat, muscle, blood vessels, nerves and tissue that surrounds bone and joints).
     

  • There are over a hundred difference types of sarcomas, and the tumors can arise anywhere in the body.
     

  • Sarcomas account for 12% of all childhood cancers (ages 0 to 14years) or 26% of childhood and adolescent cancers (0 to 19 years).
     

  • Despite the vast heterogeneity of diseases, most sarcomas are grouped into broad categories and treated with therapies not directed at the specific diseases.
     

  • Of all the pediatric cancers, sarcoma is considered one of the deadliest rare cancers, and soft tissue sarcomas are often associated with the poorest prognosis.
     

  • The cure rate for childhood cancers overall is 85%, but for sarcomas, and sarcomas similar to Parker's it is meaningfully lower.
     

  • With few exceptions, the therapies to treat sarcomas have not changed in decades.
     

  • Even when successful, the therapies to treat sarcomas are extremely toxic, and lead to lifelong morbidity. The three categories of therapy still used today are referred to by cancer doctors as cut (surgery), burn (radiation), and poison (chemotherapy).

Opportunities to make a difference

 

  • There are opportunities for improvement and examples of breakthroughs that both dramatically change the cure rate of some sarcomas, but also do so with minimal toxicity.
     

  • While there have been incredible advances and progress in survival rates of certain childhood cancer, the treatment options and improvements around pediatric sarcomas have been limited.
     

  • In short, we need better therapies for sarcoma patients.  This will only come through science and medical advances.  These will only come through passionate scientists, doctors, and support like yours. 

Little p Project is a tax-exempt 501(c)(3) nonprofit organization. Tax ID number is 88-2539807.

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